2024

Xiong R, Fleming E, Caldwell R, Vernon SD, Kozhaya L, Gunter C, Bateman L, Unutmaz D, Oh J. (2024). BioMapAI: artificial intelligence multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome. bioRxiv [Preprint]. 2024 Jun 28:2024.06.24.600378. doi.org/10.1101/2024.06.24.600378.

Vu, L. T., Ahmed, F., Zhu, H., Iu, D. S. H., Fogarty, E. A., Kwak, Y., Chen, W., Franconi, C. J., Munn, P. R., Tate, A. E., Levine, S. M., Stevens, J., Mao, X., Shungu, D. C., Moore, G. E., Keller, B. A., Hanson, M. R., Grenier, J. K., & Grimson, A. (2024). Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation. Cell Reports Medicine, 5(1), 101373. doi.org/10.1016/j.xcrm.2023.101373

Giloteaux, L., Glass, K. A., Germain, A., Franconi, C. J., Zhang, S., & Hanson, M. R. (2024). Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise. Journal of Extracellular Vesicles, 13(1), e12403. doi.org/10.1002/jev2.12403

2023

Brydges, C., Che, X., Lipkin, W. I., & Fiehn, O. (2023). Bayesian statistics improves biological interpretability of metabolomics data from human cohorts. Metabolites, 13(9), 984. doi.org/10.3390/metabo13090984

Hanson MR.2023. The viral origin of myalgic encephalomyelitis/chronic fatigue syndrome. PLoS Pathogens19(8):e1011523. doi.org/10.1371/journal.ppat.1011523

Maya J. (2023). Surveying the metabolic and dysfunctional profiles of t cells and nk cells in myalgic encephalomyelitis/chronic fatigue syndrome. International Journal of Molecular Sciences, 24(15), 11937. doi.org/10.3390/ijms241511937

Komaroff, A. L., & Lipkin, W. I. (2023). ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature. Frontiers in Medicine, 10, 1187163. doi.org/10.3389/fmed.2023.1187163

Giloteaux, L., Li, J., Hornig, M., Lipkin, W. I., Ruppert, D., & Hanson, M. R. (2023). Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls. Journal of Translational Medicine, 21(1), 322. doi.org/10.1186/s12967-023-04179-3

Vernon, S. D., Hartle, M., Sullivan, K., Bell, J., Abbaszadeh, S., Unutmaz, D., & Bateman, L. (2023). Post-exertional malaise among people with long COVID compared to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Work, 74(4), 1179-1186. doi.org/10.3233/WOR-220581

Moore, G. E., Keller, B. A., Stevens, J., Mao, X., Stevens, S. R., Chia, J. K., Levine, S. M., Franconi, C. J., & Hanson, M. R. (2023). Recovery from exercise in persons with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Medicina, 59(3), 571. doi.org/10.3390/medicina59030571

Glass, K. A., Germain, A., Huang, Y. V., & Hanson, M. R. (2023). Urine metabolomics exposes anomalous recovery after maximal exertion in female me/cfs patients. International Journal of Molecular Sciences, 24(4), 3685. doi.org/10.3390/ijms24043685

Xiong, R., Gunter, C., Fleming, E., Vernon, S. D., Bateman, L., Unutmaz, D., & Oh, J. (2023). Multi-'omics of gut microbiome-host interactions in short- and long-term myalgic encephalomyelitis/chronic fatigue syndrome patients. Cell Host & Microbe, 31(2), 273-287.e5. doi.org/10.1016/j.chom.2023.01.001

Guo, C., Che, X., Briese, T., Ranjan, A., Allicock, O., Yates, R. A., Cheng, A., March, D., Hornig, M., Komaroff, A. L., Levine, S., Bateman, L., Vernon, S. D., Klimas, N. G., Montoya, J. G., Peterson, D. L., Lipkin, W. I., & Williams, B. L. (2023). Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS. Cell Host & Microbe, 31(2), 288-304.e8. doi.org/10.1016/j.chom.2023.01.004

Nepotchatykh, E., Caraus, I., Elremaly, W., Leveau, C., Elbakry, M., Godbout, C., Rostami-Afshari, B., Petre, D., Khatami, N., Franco, A., & Moreau, A. (2023). Circulating microRNA expression signatures accurately discriminate myalgic encephalomyelitis from fibromyalgia and comorbid conditions. Scientific Reports, 13(1), 1896. doi.org/10.1038/s41598-023-28955-9

Maya, J., Leddy, S. M., Gottschalk, C. G., Peterson, D. L., & Hanson, M. R. (2023). Altered Fatty Acid Oxidation in Lymphocyte Populations of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. International Journal of Molecular Sciences, 24(3), 2010. doi.org/10.3390/ijms24032010

Oliveira, C. R., Jason, L. A., Unutmaz, D., Bateman, L., & Vernon, S. D. (2023). Improvement of Long COVID symptoms over one year. Frontiers in Medicine, 9, 1065620. doi.org/10.3389/fmed.2022.1065620

2022

Ahmed F, Vu LT, Zhu H, Iu DSH, Fogarty EA, Kwak Y, Chen W, Franconi, CJ, Munn PR, Levine SM, Stevens J, Mao X, Shung DC, Moore GE, Keller BA, Hanson MR, Grenier JK, & Grimson A. 2022. Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation. bioRxiv 2022.10.13.512091. doi.org/10.1101/2022.10.13.512091

Goldberg, N. C., Poirier, S., Kanas, A., McCorkell, L., McGinn, C. A., Re'em, Y., Kuehnel, K., Muirhead, N., Ruschioni, T., Taylor-Brown, S., & Jason, L. A. (2022). A new clinical challenge: Supporting patients coping with the long-term effects of COVID-19. Fatigue: Biomedicine, Health & Behavior, 1-19. doi.org/10.1080/21641846.2022.2128576

Ramiller, A., Mudie, K., Seibert, E., & Whittaker, S. (2022). The Facilitation of Clinical and Therapeutic Discoveries in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Related Diseases: Protocol for the You + ME Registry Research Platform. JMIR research protocols, 11(8), e36798. doi.org/10.2196/36798

Che X., Brydges C.R., Yu Y., Price A., Joshi S., Roy A., Lee B., Barupal D.K., Cheng A., Palmer D.M., Levine S., Peterson D.L., Vernon S.D., Bateman L., Hornig M., Montoya J.G., Komaroff A.L., Fiehn O., Lipkin W.I. Metabolomic Evidence for Peroxisomal Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. International Journal of Molecular Sciences. 2022; 23(14):7906. doi.org/10.3390/ijms23147906

Vernon, S. D., Funk, S., Bateman, L., Stoddard, G. J., Hammer, S., Sullivan, K., Bell, J., Abbaszadeh, S., Lipkin, W. I., & Komaroff, A. L. (2022). Orthostatic Challenge Causes Distinctive Symptomatic, Hemodynamic and Cognitive Responses in Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Frontiers in Medicine. 9;917019. doi.org/10.3389/fmed.2022.917019

O'Neal A. J., Glass K. A., Emig C. J., Vitug A. A., Henry S. J., Shungu D. C., Mao X., Levine S. M., Hanson M. R. (2022). Survey of anti-pathogen antibody levels in myalgic encephalomyelitis/chronic fatigue syndrome, Proteomes, 10 (2), 21. doi.org/10.3390/proteomes10020021

Germain, A., Giloteaux, L., Moore, G. E., Levine, S. M., Chia, J. K., Keller, B. A., Stevens, J., Franconi, C. J., Mao, X., Shungu, D. C., Grimson, A., and Hanson, M. R. (2022). Plasma metabolomics reveals disrupted response and recovery following maximal exercise in myalgic encephalomyelitis/chronic fatigue syndrome. JCI Insight, 7(9), e157621. doi.org/10.1172/jci.insight.157621

2021

Mathur, R., Carnes, M. U., Harding, A., Moore, A., Thomas, I., Giarrocco, A., Long, M., Underwood, M., Townsend, C., Ruiz-Esparza, R., Barnette, Q., Brown, L. M., Schu, M. (2021). mapMECFS: A portal to enhance data discovery across biological disciplines and collaborative sites. Journal of Translational Medicine, 19(1), 461. doi:10.1186/s12967-021-03127-3

Paul, B. D., Lemle, M. D., Komaroff, A. L., and Snyder, S. H. (2021). Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome. Proceedings of the National Academy of Sciences - PNAS, 118(34), 1. doi:10.1073/pnas.2024358118

Hanson, M. R. (2021, August 12). Are enteroviruses behind mysterious outbreaks of chronic fatigue syndrome? Frontiers Science News.

O'Neal, A. J., and Hanson, M. R. (2021). The enterovirus theory of disease etiology in myalgic encephalomyelitis/chronic fatigue syndrome: A critical review. Frontiers in Medicine, 8, 688486. doi:10.3389/fmed.2021.688486

E Komaroff, A. L., and Lipkin, W. I. (2021). Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome. Trends in Molecular Medicine, 27(9), 895-906. doi:10.1016/j.molmed.2021.06.002

E Zhang, D. X., Vu, L. T., Ismail, N. N., Le, M., and Grimson, A. (2021). Landscape of extracellular vesicles in the tumour microenvironment: Interactions with stromal cells and with non-cell components, and impacts on metabolic reprogramming, horizontal transfer of neoplastic traits, and the emergence of therapeutic resistance. Seminars in Cancer Biology, 74, 24-44. doi.org/10.1016/j.semcancer.2021.01.007

Germain, A., Levine, S. M., and Hanson, M. R. (2021). In-depth analysis of the plasma proteome in ME/CFS exposes disrupted ephrin-eph and immune system signaling. Proteomes, 9(1), 6. doi:10.3390/proteomes9010006

2020

Nepotchatykh, E., Elremaly, W., Caraus, I., Godbout, C., Leveau, C., Chalder, L., Beaudin, C., Kanamaru, E., Kosovskaia, R., Lauzon, S., Maillet, Y., Franco, A., Lascau-Coman, V., Bouhanik, S., Gaitan, Y. P., Li, D., and Moreau, A. (2020). Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease pathophysiology. Scientific Reports, 10(1), 19620. doi:10.1038/s41598-020-76438-y

Giloteaux, L., O'Neal, A., Castro-Marrero, J., Levine, S. M., and Hanson, M. R. (2020). Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: A pilot study. Journal of Translational Medicine, 18(1), 387. doi:10.1186/s12967-020-02560-0

Lee, J., Vernon, S. D., Jeys, P., Ali, W., Campos, A., Unutmaz, D., Yellman, B., Bateman, L. (2020). Hemodynamics during the 10-minute NASA lean test: Evidence of circulatory decompensation in a subset of ME/CFS patients. Journal of Translational Medicine, 18(1), 314. doi:10.1186/s12967-020-02481-y

Milivojevic, M., Che, X., Bateman, L., Cheng, A., Garcia, B. A., Hornig, M., Huber, M., Klimas, N. G., Lee, B., Lee, H., Levine, S., Montoya, J. G., Peterson, D. L., Komaroff, A. L., and Lipkin, W. I. (2020). Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS. PloS One, 15(7), e0236148. doi:10.1371/journal.pone.0236148

Hanson, M. R., and Germain, A. (2020). Letter to the Editor of Metabolites. Metabolites, 10(5), 216. doi.org/10.3390/metabo10050216

Mandarano, A. H., Maya, J., Giloteaux, L., Peterson, D. L., Maynard, M., Gottschalk, C. G., and Hanson, M. R. (2020). Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations. The Journal of Clinical Investigation, 130(3), 1491-1505. doi:10.1172/JCI132185

Germain, A., Barupal, D. K., Levine, S. M., and Hanson, M. R. (2020). Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl lipids and steroids. Metabolites, 10(1), 34. doi:10.3390/metabo10010034

2019

Oh, J., and Unutmaz, D. (2019). Immune cells for microbiota surveillance. Science (American Association for the Advancement of Science), 366(6464), 419-420. doi:10.1126/science.aaz4014

Friedman, K. J., Bateman, L., Bested, A., and Nahle, Z. (2019). Editorial: Advances in ME/CFS research and clinical care. Frontiers in Pediatrics, 7, 370. doi:10.3389/fped.2019.00370

Komaroff, A. L. (2019). Advances in understanding the pathophysiology of chronic fatigue syndrome. JAMA : The Journal of the American Medical Association, 322(6), 499-500. doi:10.1001/jama.2019.8312