ME/CFS Can Affect Anyone

Millions of people worldwide are affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Yet the causes, diagnostic markers, progression, and FDA-approved treatments remain unknown. The shared vision of the ME/CFS Collaborative Research Network (ME/CFSnet) is to encourage collaborative research in partnership with individuals and advocacy groups to understand the disease and develop better diagnosis and treatment.


New Publication! MECFS Network Investigators Further Elucidate Potential ME/CFS Biomarkers

February 8, 2023

Two new studies published in Cell Host & Microbe link altered gut microbiome to ME/CFS. MECFSnet investigators Dr. Julia Oh and Dr. Derya Unutmaz examine host-microbiome interactions in ME/CFS and potential metabolic consequences. These findings, along with a study by Dr. Brent L Williams and Dr. Ian Lipkin, add to growing evidence that the microbiome could provide biomarkers for ME/CFS.

Take Me There


New Publication! New Research Links Altered Gut Microbiome to ME/CFS

February 8, 2023

Research by MECFSnet investigators Dr. Brent L Williams and Dr. Ian Lipkin found that people with ME/CFS have significant gut microbiome dysbiosis. These findings, along with a study by Dr. Julia Oh and Dr. Derya Unutmaz were published in Cell Host & Microbe. This research suggests that certain differences in gut microbiome may serve as ME/CFS biomarkers.

Take Me There


New Publication! MECFSnet Investigators Use Circulating miRNA to Distinguish ME/CFS from Fibromyalgia

February 2, 2023

New research published in Scientific Reports found that 11 miRNAs were different in people with ME/CFS and fibromyalgia. These miRNAs were also used to successfully distinguish between ME/CFS and fibromyalgia. These findings can help diagnose and treat individuals with ME/CFS.

Take Me There

A Network to Unite

These institutions are working together as the ME/CFS Research Network.

Visit the CDC to learn more about ME/CFS.

Join the Quest for Discoveries

The experience and expertise of every individual helps provide a better understanding of ME/CFS. Learn more about how you can become a part of this collaborative effort.

Collaboration Drives Progress

Investigators, health care providers, and advocates are collaborating across the Research Network to drive progress in understanding ME/CFS. Together, we can advance discoveries to improve the lives of members of the ME/CFS community.

Grants that fund MECFSnet are managed by the National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases and the National Institute of Neurological Disorders and Stroke. This website was supported by a grant from NIH, grant #U24-NS-105535.

Logo for National Institute of Health (NIH)

Website design and development by RTI International. RTI is a registered trademark and trade name of Research Triangle Institute. The RTI logo is a registered trademark of Research Triangle Institute.

Logo for RTI International

What is ME/CFS?

Myalgic Encephalomyelitis (ME), also referred to as Chronic Fatigue Syndrome (CFS), is a multi-system disease that causes dysfunction of the neurological, immune, endocrine, and energy metabolism systems.