ME/CFS Can Affect Anyone

Millions of people worldwide are affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Yet the causes, diagnostic markers, progression, and FDA-approved treatments remain unknown. The shared vision of the ME/CFS Collaborative Research Network (ME/CFSnet) is to encourage collaborative research in partnership with individuals and advocacy groups to understand the disease and develop better diagnosis and treatment.


New Publication! MECFS Network Investigators Leverage Multiple Datasets to Identify ME/CFS

May 23, 2023

New research published in the Journal of Translational Medicine distinguishes individuals with ME/CFS from healthy controls with 86% accuracy. These findings are the result of a collaboration between two of our Network's research centers: Cornell University's Center for Enervating Immune Disease and Columbia's Center for Solutions for ME/CFS.

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New Publication! MECFS Network Investigators Examine Recovery from Exercise in ME/CFS

March 29, 2023

New research from MECFSnet investigators examines recovery from post exercise malaise in ME/CFS. These findings provide robust support cautioning against the use of graded exercise therapy in individuals with ME/CFS. This study was published in Medicina.

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National Geographic Article Features Microbiome Findings from Two MECFSnet Investigators

March 23, 2023

New research from MECFSnet investigators at Columbia's Center for Solutions for ME/CFS and the Jackson Laboratory suggest changes in gut microbiome might be the cause of ME/CFS. These findings may hold the key for new way to diagnose and treat ME/CFS. These studies were published in Cell Host & Microbe.

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A Network to Unite

These institutions are working together as the ME/CFS Research Network.

Visit the CDC to learn more about ME/CFS.

Join the Quest for Discoveries

The experience and expertise of every individual helps provide a better understanding of ME/CFS. Learn more about how you can become a part of this collaborative effort.

Collaboration Drives Progress

Investigators, health care providers, and advocates are collaborating across the Research Network to drive progress in understanding ME/CFS. Together, we can advance discoveries to improve the lives of members of the ME/CFS community.

Grants that fund MECFSnet are managed by the National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases and the National Institute of Neurological Disorders and Stroke. This website was supported by a grant from NIH, grant #U24-NS-105535.

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What is ME/CFS?

Myalgic Encephalomyelitis (ME), also referred to as Chronic Fatigue Syndrome (CFS), is a multi-system disease that causes dysfunction of the neurological, immune, endocrine, and energy metabolism systems.