ME/CFS Can Affect Anyone

Millions of people worldwide are affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Yet the causes, diagnostic markers, progression, and FDA-approved treatments remain unknown. The shared vision of the ME/CFS Collaborative Research Network (ME/CFSnet) is to encourage collaborative research in partnership with individuals and advocacy groups to understand the disease and develop better diagnosis and treatment.

NEWS

Discover the UK ME/CFS Biobank

July 24, 2025

The UK ME/CFS Biobank stores over 30,000 aliquots of blood samples and data generously donated by >600 donors including people living with mild/moderate and severe ME/CFS, with multiple sclerosis (MS), and healthy controls. Participants with ME/CFS have longitudinal samples at up to 6 timepoints. Researchers can access high-quality blood samples and data from the biobank free of charge for a limited time.

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NEWS

New Publication! Post-exercise Proteomics Reveal Biological Disruptions in Men with ME/CFS

July 3, 2025

New research from MECFSnet investigators provides insights into the molecular basis of PEM and suggests potential targets to improve recovery and energy metabolism in ME/CFS. This study was published in Clinical and Translational Medicine.

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NEWS

New Publication! New Study Examines Autoantibody Immune Profiles in ME/CFS

June 13, 2025

New research from MECFSnet investigators found no significant differences in autoantibody immune profiles among people with ME/CFS and healthy people. However, there were subtle differences in autoantibody ratios between male and females. This research was published in the International Journal of Molecular Science.

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A Network to Unite

These institutions are working together as the ME/CFS Research Network.

Visit the CDC to learn more about ME/CFS.

Join the Quest for Discoveries

The experience and expertise of every individual helps provide a better understanding of ME/CFS. Learn more about how you can become a part of this collaborative effort.

Collaboration Drives Progress

Investigators, health care providers, and advocates are collaborating across the Research Network to drive progress in understanding ME/CFS. Together, we can advance discoveries to improve the lives of members of the ME/CFS community.

Grants that fund MECFSnet are managed by the National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases and the National Institute of Neurological Disorders and Stroke. This website was supported by a grant from NIH, grant #U24-NS-105535.

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Website design and development by RTI International. RTI is a registered trademark and trade name of Research Triangle Institute. The RTI logo is a registered trademark of Research Triangle Institute.

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What is ME/CFS?

Myalgic Encephalomyelitis (ME), also referred to as Chronic Fatigue Syndrome (CFS), is a multi-system disease that causes dysfunction of the neurological, immune, endocrine, and energy metabolism systems.