ME/CFS Can Affect Anyone

Millions of people worldwide are affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Yet the causes, diagnostic markers, progression, and FDA-approved treatments remain unknown. The shared vision of the ME/CFS Collaborative Research Network (ME/CFSnet) is to encourage collaborative research in partnership with individuals and advocacy groups to understand the disease and develop better diagnosis and treatment.

EVENT

ICanCME Canadian Collaborative Conference on ME

October 29, 2025

Mark your calendars for the ICanCME Canadian Collaborative Conference on ME: Nothing About Us Without Us. This virtual 3-day event is free to attend: November 4-6. Register today!

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EVENT

2025 IACFS Conference

September 10, 2025

Mark your calendars for the International Association for IACFS/ME Virtual Research and Medical Conference from October 22-25. Register today!

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NEWS

New Publication! New Study Examines Immune Response in ME/CFS Pre/Post Exercise

September 3, 2025

New research from MECFSnet investigators at Columbia's Center for Solutions for ME/CFS finds heightened innate immunity may trigger chronic inflammation, fatigue, and post-exertional malaise in MECFS. This study was published in npj Metabolic Health and Disease.

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A Network to Unite

These institutions are working together as the ME/CFS Research Network.

Visit the CDC to learn more about ME/CFS.

Join the Quest for Discoveries

The experience and expertise of every individual helps provide a better understanding of ME/CFS. Learn more about how you can become a part of this collaborative effort.

Collaboration Drives Progress

Investigators, health care providers, and advocates are collaborating across the Research Network to drive progress in understanding ME/CFS. Together, we can advance discoveries to improve the lives of members of the ME/CFS community.

Grants that fund MECFSnet are managed by the National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases and the National Institute of Neurological Disorders and Stroke. This website was supported by a grant from NIH, grant #U24-NS-105535.

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What is ME/CFS?

Myalgic Encephalomyelitis (ME), also referred to as Chronic Fatigue Syndrome (CFS), is a multi-system disease that causes dysfunction of the neurological, immune, endocrine, and energy metabolism systems.